2019鑷€冦€婅棩鐞嗗(xu茅)(涓€)銆嬮洠榛�(di菐n)绛嗚(浜�)


2019鑷€冦€婅棩鐞嗗(xu茅)(涓€)銆嬮洠榛�(di菐n)绛嗚(浜�)
(鍗�)瑙i噵涓嬪垪鍚嶈锛�
1銆侀閬�(gu貌)娑堥櫎锛氫富瑕佸湪鑲濊嚐浠h瑵鐨勮棩鐗╋紝鍙f湇绲﹁棩鍚�锛屽湪閫�(j矛n)鍏ラ珨寰挵(hu谩n)涔嬪墠锛岄儴鍒嗗湪鑳冭吀绮樿啘鍙婅倽鑷熻婊呮椿锛岀ū涔嬨€傞閬�(gu貌)娑堥櫎鐜囬珮鑰�锛屽彛鏈嶅惛鏀跺樊銆�
2銆佺敓鐗╁埄鐢ㄥ害锛氱稉(j墨ng)閬�(gu貌)鏈夊惛鏀堕亷(gu貌)绋�(闄ら潨鑴堢郸钘ュ)鐨勯€斿緫锛岀敤钘ュ悗鍒伴仈(d谩)楂斿惊澹炵殑鐩稿皪(du矛)閲忓拰鐩稿皪(du矛)閫熷害銆傚畠鍙互瑭�(p铆ng)鍍�(ji脿)钘ョ墿鍒跺姂鐨勮唱(zh矛)閲�锛屽苟涓斿弽鏄犺棩鐗╁惛鏀堕€熷害灏�(du矛)钘ユ晥鐨勫奖闊裤€�
3銆佽〃瑙€鍒嗗竷瀹圭⿳(VD)锛氭寚闈滆剤娉ㄥ皠涓€瀹氶噺钘ョ墿A锛屽緟鍒嗗竷骞宠 鍚�锛屾寜娓�(c猫)寰楃殑琛€婕挎韩搴�(CP)瑷�(j矛)绠楄┎钘ユ噳(y墨ng)鍗犳湁鐨勮婕垮绌�锛孷D=A/CP锛屽畠鍙互浼拌▓(j矛)钘ョ墿鍒嗗竷鐗归粸(di菐n)鍜岀敤浜庤▓(j矛)绠楁湁闂�(gu膩n)钘ュ嫊(d貌ng)瀛�(xu茅)鍙冩暩(sh霉)銆�
4銆佹竻闄ょ巼(CL)锛氭寚鍠綅鏅�(sh铆)闁撳収(n猫i)澶氬ぇ瀹圭⿳琛€婕夸腑鐨勮棩鐗╂秷闄わ紝CL鏄竴甯告暩(sh霉)锛屽父鐢ㄤ簬浼板児(ji脿)钘ョ墿娑堥櫎鎯呮硜鍜岀郸钘ラ€熺巼鐨勮▓(j矛)绠椼€�
5銆佹秷闄ゅ崐琛版湡(+1/2)锛氫竴鑸寚琛€婕胯棩鐗╂績搴︽秷闄や竴鍗婃墍闇€瑕佺殑鏅�(sh铆)闁�锛屽嵆琛€婕挎秷闄ゅ崐琛版湡锛岀敤浜庝及瑷�(j矛)钘ョ墿鐨勬秷闄ゅ拰钃勭⿳鎯呮硜浠ュ強鍚嶇ó钘ュ嫊(d貌ng)瀛�(xu茅)鍙冩暩(sh霉)銆�
(鍗佷竴)涓€绱�(j铆)鐨勯浂绱�(j铆)鍕�(d貌ng)鍔涘(xu茅)娑堥櫎閬�(gu貌)绋嬬殑鐗归粸(di菐n)
涓€绱�(j铆)鍕�(d貌ng)鍔涘(xu茅)娑堥櫎閬�(gu貌)绋嬬壒榛�(di菐n)锛�1銆佸湪鍠綅鏅�(sh铆)闁撻噷锛岄珨鍏�(n猫i)钘ョ墿鎸夋亽瀹氱殑姣斾緥琛版笡锛屽張绋辨亽姣旀秷闄�銆�2銆佽婕胯棩涓€鏅�(sh铆)鏇茬窔鍦ㄦ績搴﹀彇灏�(du矛)鏁�(sh霉)鏅�(sh铆)鐐轰竴鐩寸窔銆�3銆佽婕挎秷闄ゅ崐琛版湡鏄竴鎭掓暩(sh霉)銆�4銆佹亽閫�銆佹亽閲忕郸钘�锛岀稉(j墨ng)4-5鍊�(g猫)鍗婅“鏈熼仈(d谩)鍒扮┅(w臎n)鎱�(t脿i)婵冨害銆�
闆剁礆(j铆)鍕�(d貌ng)鍔涘(xu茅)娑堥櫎閬�(gu貌)绋嬬壒榛�(di菐n)锛�1銆佸柈浣嶆檪(sh铆)闁撻噷鎸夋亽瀹氱殑閲忚“娓�锛屽張绋辨亽閲忔秷闄�銆�2銆佽婕胯棩鏅�(sh铆)鏇茬窔婵冨害鍙栫畻琛�(sh霉)鍒诲害鏅�(sh铆)鏄竴姊濈洿绶�銆�3銆佽婕挎秷闄ゅ崐琛版湡涓嶆槸涓€甯告暩(sh霉)銆�4銆佸弽寰�(f霉)绲﹁棩锛岀悊璜栦笂鐒�(w煤)绌�(w臎n)鎱�(t脿i)婵冨害锛屾槗钃勭⿳涓瘨銆�
浜屻€佹姉鑿岃棩鐗�
(涓€)瑙i噵涓嬪垪鍚嶈
1銆佸寲瀛�(xu茅)娌荤檪锛氬皪(du矛)楂斿収(n猫i)鐥呭師寰敓鐗�銆佸瘎鐢熻煵(ch贸ng)銆佹儭鎬ц叓鐦ゆ墍鑷寸柧鐥呯殑钘ョ墿娌荤檪銆�
2銆佸寲鐧傛寚鏁�(sh霉)锛氬嵆鍖栧(xu茅)娌荤檪钘ョ墿鐨凩D50/ED50銆侺D50鏄嫊(d貌ng)鐗╁崐鏁�(sh霉)鑷存閲忥紝ED50鏄不鐧傛劅鏌撳嫊(d貌ng)鐗╃殑鍗婃暩(sh霉)鏈夋晥閲�;鍖栫檪鎸囨暩(sh霉)鎰堝ぇ锛岃〃鏄庤棩鐗╂瘨鎬ф剤灏忥紝鐩稿皪(du矛)杓冨畨鍏�锛屼絾骞堕潪绲曞皪(du矛)瀹夊叏锛屽鍖栫檪鎸囨暩(sh霉)楂樼殑闈掗湁绱犲彲鑷撮亷(gu貌)鏁忔€т紤鍏�銆�
3銆佹姉鑿岃瓬锛氭寚鏌愮ó鎶楄弻钘ョ墿鎶戝埗鎴栨婊呯梾鍘熷井鐢熺墿鐨勮寖鍦�銆�
4銆佹姉鑿屾椿鎬ф寚妯�(bi膩o)锛�
(1)鏈€浣庢姂鑿屾績搴IC锛氬湪楂斿瑭﹂(y脿n)涓�锛屾姂鍒跺煿椁�(y菐ng)鍩哄収(n猫i)绱�(x矛)鑿岀敓闀�(zh菐ng)鐨勬渶浣庢績搴︺€�
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(浜�)鎶楄憠閰镐唬璎濓細2銆佹姂鍒剁窗(x矛)鑿岀窗(x矛)鑳炲鍚堟垚;3銆佸奖闊胯優婕胯啘鐨勯€氶€忔€�;4銆佹姂鍒惰泲鐧借唱(zh矛)鍚堟垚;5銆佹姂鍒舵牳闆欎唬璎�銆�
(涓�)绱�(x矛)鑿岃€愯棩鎬х敘(ch菐n)鐢熺殑姗�(j墨)鍒�;
1銆佺敘(ch菐n)鐢熸粎娲婚叾;2銆佹敼璁婄窗(x矛)鑿岃優婕胯啘閫氶€忔€�;3銆佺窗(x矛)鑿岄珨鍏�(n猫i)闈朵綅绲�(ji茅)妲�(g貌u)鐨勬敼璁�;4銆佹敼璁婅弻楂斿収(n猫i)浠h瑵閫斿緫銆�
(鍥�)璜炬盁鏄熺殑鐗归粸(di菐n)锛�
1銆佹姉鑿屼綔鐢細寤h瓬鎶楄弻钘�锛屽皪(du矛)闈╄槶姘忛櫚鎬ц弻澶ц吀妗胯弻锛岃畩褰㈡】鑿岀殑鎶楄弻浣滅敤寮�(qi谩ng)澶э紝灏�(du矛)鑰愰潚闇夌殑娣嬬悆鑿屾晱鎰�锛屼笉鏄撶敘(ch菐n)鐢熻€愯棩鎬э紝鍜屽叾浠栨姉鐢熺礌?z茅)o浜ゅ弶鑰愬彈鎬�銆�
2銆佹姉鑿屾(j墨)鍒讹細鎶戝埗绱�(x矛)鑿岀殑CNA鍥炴棆閰惰€屾姂鍒禗NA鐨勫悎鎴�銆�
3銆佽嚚搴婃噳(y墨ng)鐢細鐢ㄤ簬鏁忔劅鑿屽紩璧风殑娉屽翱閬�銆佽儍鑵搁亾銆佸懠鍚搁亾鎰熸煋鍜屾穻鐥呯殑娌荤檪銆�4銆佹湁涓鎶戝埗锛岃儍鑵搁亾鍙嶆噳(y墨ng)锛岀毊鐤圭瓑锛屾厧鐢ㄤ簬瀛曞│銆佸摵涔虫湡濠﹀コ銆佸辜榻″厭绔ワ紝銆傚洜?q奴)顬嬭緰M绻斾笉鑹奖闊�锛岀鐢ㄤ簬鏈钘ラ亷(gu貌)鏁�
(浜�)鐢茬鍞戠殑浣滅敤銆佹噳(y墨ng)鐢ㄥ強涓嶈壇鍙嶆噳(y墨ng)銆�
1銆佺偤纭濊崈鍜攽椤炶棩鐗╋紝鏈夊唬璀滄姉鍘哀鑿屼綔鐢�锛屽皪(du矛)鎵€鐢ㄥ幁姘х悆鑿�銆侀潻铇皬闄版€у幁姘ф】鑿�銆侀潻铇皬闄�(y谩ng)鎬ц娊鑳炴】鑿屾湁鏁�锛屼絾灏�(du矛)闈╄槶姘忛櫧(y谩ng)鎬х劇(w煤)鑺借優妗胯弻鐒�(w煤)鏁�;鑷ㄥ簥鐢ㄤ簬涓婅堪绱�(x矛)鑿屾墍鑷存劅鏌�锛�2銆佹姉闄伴亾婊磋煵(ch贸ng)鐨勯閬歌棩銆�3銆佹姉闃跨背宸村師锜�(ch贸ng)锛屽皪(du矛)鑵稿収(n猫i)銆佽吀鑳冨闃跨背宸撮兘鏈夐’钁楃檪鏁堬紝灏�(du矛)鐒�(w煤)鐧ョ媭鎺掑寘鍥婅€呯檪鏁堝樊銆�4銆佷笉鑹弽鎳�(y墨ng)杓曞井锛屽父瑕�(ji脿n)鑳冭吀閬撳弽鎳�(y墨ng)锛屾姂鍒朵箼閱囪瑵锛屼腑妯炵缍�(j墨ng)鐤剧梾锛岃娑茬梾鎮h€呮姉鑿岄濡婂鏃╂湡濠﹀コ绂佺敤銆�
(鍏�)闈掗湁绱燝鐨勬姉鑿屼綔鐢ㄧ壒榛�(di菐n)鍙婅嚚搴婃噳(y墨ng)鐢�銆�
鎶楄弻浣滅敤鐗归粸(di菐n)锛�1銆佹姉鑿屼綔鐢細鐐虹獎璀滄姉鑿岀礌锛屽皪(du矛)闈╄槶姘忛櫧(y谩ng)鎬х悆鑿�銆佹】鑿屽強闈╄槶姘忛櫚鎬х悆鑿屾湁寮�(qi谩ng)澶х殑娈鸿弻浣滅敤锛屽皪(du矛)铻烘棆楂�銆佸叆绶氳弻涔熸湁鏁�锛屽皪(du矛)闈╄槶姘忛櫚鎬ф】鑿屼綔鐢ㄨ純寮便€�2銆佷綔鐢ㄦ(j墨)鍒讹細鍙垏绱�(x矛)鑿岃優婕胯啘涓婄殑闈掗湁绱犵祼(ji茅)鍚堣泲鐧絇BPS绲�(ji茅)鍚�锛屾姂鍒惰弻楂旂矘鑲藉悎鎴愶細娲诲寲鑷憾閰�锛屽皫(d菐o)鑷寸窗(x矛)鑿屾浜�銆�3銆佽€愯棩鎬�;闈掗湁绲�(ji茅)妲�(g貌u)涓殑β-鍏�(n猫i)閰拌兒鐞�?y脿n)姒挄顚婇挌杩愵姠鍖�?锛屾槗?beta;-鍏�(n猫i)閰拌兒閰惰瑙h€屽け娲汇€傞€欐槸绱�(x矛)鑿岀敘(ch菐n)鐢熻€愯棩鎬х殑涓昏鍘熷洜涔嬩竴
鑷ㄥ簥鎳�(y墨ng)鐢細涓昏鐢ㄤ簬鍚勭ó鐞冭弻銆侀潻铇皬闄�(y谩ng)鎬ф】鑿屽強铻烘棆楂旀墍鑷寸殑灞€閮ㄧ祫绻斿強鍏ㄨ韩鎰熸煋銆�
(涓�)闈掗湁绱燝鐨勪笉鑹弽鎳�(y墨ng)鍙婇槻娌�銆�
1銆佽〃鐝�(xi脿n)锛氭渶甯歌(ji脿n)鐨勪笉鑹弽鎳�(y墨ng)鐐洪亷(gu貌)鏁忓弽鎳�(y墨ng)锛屽毚(y谩n)閲嶈€呯偤閬�(gu貌)鏁忔€т紤鍏�銆�
2銆佹不鐧傦細鎼舵晳涓栦富鏅�(sh铆)锛屽彲鐨笅鎴栬倢鑲夋敞灏勮厧涓婅吅绱狅紝蹇呰鏅�(sh铆)鍙珐鎱㈤潨鑴堟敞灏勬垨闈滆剤婊存敞锛岄倓鍙姞鐢ㄧ硸婵€绱犲強HI鍙楅珨闃绘柗钘�銆�
3銆侀爯(y霉)闃叉帾鏂斤細1)瑭崇窗(x矛)瑭㈠晱(w猫n)閬�(gu貌)鏁忓彶锛屾湁闈掗湁绱犻亷(gu貌)鏁忚€呯鐢�;2)娉ㄥ皠鍓嶆噳(y墨ng)浣滅毊瑭�;3)钘ユ恫蹇呴爤鑷ㄦ檪(sh铆)閰嶅埗;4)閬垮厤鍦ㄩ亷(gu貌)搴﹂椁撴檪(sh铆)鐢ㄨ棩锛屾敞灏勫悗瑙€瀵熷崐灏忔檪(sh铆);5)鎳�(y墨ng)浣滃ソ鎼舵晳婧�(zh菙n)鍌�;6)鎺屾彙閬╂噳(y墨ng)璀�锛岄伩鍏嶅眬閮ㄧ敤钘�銆�
(鍏�)闋鑿岀礌鐨勬姉鑿岀壒榛�(di菐n)銆�
鎶楄弻娲绘€ц崈鍦�(tu谩n)涔熺偤β-鍏�(n猫i)閰拌兒澹烇紝浣滅敤姗�(j墨)鍒惰垏闈掗湁绱犵浉浼�銆傚叾鎶楄弻璀滃唬锛屾鑿屽姏寮�(qi谩ng)锛屽皪(du矛)β-鍏�(n猫i)閰拌兒閰惰純绌�(w臎n)瀹氾紝閬�(gu貌)鏁忓弽鎳�(y墨ng)灏�(鑸囬潚闇夌礌椤炲儏鏈夐儴鍒嗕氦鍙夐亷(gu貌)鏁忕従(xi脿n)璞�)銆�
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