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銆€銆€Once-daily Pill Could Simplify HIV Treatment

銆€銆€Bristol-Myers Myers Squibb and Gilead Sciences have combined many HIV drugs into a single pill Sometimes the best medicine is more than one kind of medicine. Malaria, tuberculosis and HIV/AIDS,2 for example, are all treated with ____1____ of drugs. But that can mean a lot of pills to take. It would be ____2____ if drug companies combined all the medicines into a single pill, taken just once a day.

銆€銆€Now, two companies say they have done that for people just ____3____ treatment for HIV, the virus that causes AIDS. The companies are Bristol-Myers Squibb and Gilead Sciences. They have ____4____ a single pill that combines three drugs currently on the market.3 Bristol-Myers Squibb sells one of them ____5____ the name of Sustiva.4 Gilead combined the ____6____, Emtriva and Viread, into a single pill in two thousand four.

銆€銆€Combining drugs involves more than ____7____ issues. It also involves issues of competition ____8____ the drugs are made by different companies. The new once-daily pill is the result of ____9____ is described as the first joint venture agreement of its kind in the treatment of HIV

銆€銆€In January the New England Journal of Medicine5 published a study of the new pill. Researchers compared its ____10____ to6 that of the widely used combination of Sustiva and Combivir. Combivir ____11____ two drugs, AZT7 and 3TC.8 The researchers say that after one year of treatment, the new pill suppressed HIV levels in more patients and with ____12____ side effects.9 Gilead paid for the study. Professor Joel Gallant at the Johns Hopkins School of Medicine in Baltimore, Maryland, led the research. He is a paid adviser to Gilead and Bristol-Meyers Squibb as well as the maker of Combivir, GlaxoSmithKline.

銆€銆€Glaxo Smith Kline reacted ____13____ the findings by saying that a single study is of limited value. It says the effectiveness of Combivir has been shown in each of more than fifty studies.

銆€銆€The price of the new once-daily pill has not been announced. But Gilead and Bristol-Myers Squibb say they will provide it at reduced cost to developing countries. They plan in the next few months to ask the United States Food and Drug Administration10 to ____14____ the new pill.

銆€銆€There are limits to who could take it because of the different drugs it contains. For example, ____15____ women are told not to take Sustiva because of the risk of birth disorders.11 Experts say more than forty million people around the world are living with HIV

銆€銆€1. A) conservation B) cooperation C) combinations D) considerations

銆€銆€2. A) simpler B) more complex C) more meaningless D) more troublesome

銆€銆€3. A) starting B) stopping C) ending D) discontinuing

銆€銆€4. A) analyzed B) examined C) explored D) developed

銆€銆€5. A) before B) after C) under D) above

銆€銆€6. A) one B) ones C) other D) others

銆€銆€7. A) social B) technical C) personal D) historical

銆€銆€8. A) if B) as if C) though D) as though

銆€銆€9. A) that B) which C) what D) whatever

銆€銆€10. A) size B) shape C) appearance D) effectiveness

銆€銆€11. A) excludes B) contains C) looks like D) tastes of

銆€銆€12. A) few B) fewer C) many D) more

銆€銆€13. A) for B) with C) to D) into

銆€銆€14. A) prove B) disprove C) improve D) approve

銆€銆€15. A) weak B) strong C) elder D) pregnant

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